Monday, May 16, 2022

Time Event (+)
09:00 - 09:15 INTRODUCTION - Véronique Maguer-Satta and Claire Chazaud  
09:15 - 12:15 DEVELOPMENT AND REGULATION OF STEM CELL FATE - Chairs: Claire Chazaud and Olivier Raineteau  
09:15 - 09:45 Endocrine control of the mammary stem cell - Katrin Brisken, EPFL, Lausanne  
09:45 - 10:15 Mechanisms Underlying Adult Neural Stem Cell Quiescence Exit - Darcie Moore, University of Wisconsin - Madison  
10:15 - 10:30 Calcium signals triggered by the microenvironment regulate stem cell self-renewal: from adult neural stem cells to glioblastoma stem cells. - Valérie Coronas, Laboratoire 4CS, Poitiers - Selected talk  
10:30 - 11:00 COFFEE BREAK  
11:00 - 11:15 Neonatal brain injury unravels transcriptional and signaling changes underlying neural stem cell regenerative potential in the postnatal subventricular zone - Louis Foucault, Stem Cell and Brain Research Institute, Bron - Selected talk  
11:15 - 11:45 Mechanical feedback in embryonic self-organization - Jérôme Gros, Institut Pasteur, Paris  
11:45 - 12:15 New insight into the heterogeneity of HSCs and their clonal evolution during aging - Estelle Duprez, Centre de recherche en cancérologie, Marseille  
12:15 - 14:00 LUNCH & FREE VISIT OF POSTERS  
14:00 - 16:00 TUMORIGENESIS AND CANCER PROGRESSION - Chairs: Nathalie Mazure and Claude Caron de Fromentel  
14:00 - 14:30 Drivers of Spontaneous Stem Cell Mutation - Allison Bardin, Curie Institute, Paris  
14:30 - 15:00 Molecular mechanisms of brain tumor initiation and progression - Frédéric Charron, Institut de Recherches Cliniques de Montréal  
15:00 - 15:15 ACLY defines a therapeutic vulnerability in PTEN-null T-ALL - Melania Tesio, Laboratory of Onco-Hematology, Paris - Selected talk  
15:15 - 15:30 Control of disseminated breast cancer cell dormancy in the bone marrow by TGFB2 and BMP4 signaling - Emma Risson, Centre de Recherche en Cancerologie de Lyon - Selected talk  
15:30 - 16:00 A Single Coactivator Simplifies Cancer to Binary Classes that Interchange to Evade Therapy - Rod Bremner, Lunenfeld-Tanenbaum Research Institute, Toronto  
16:00 - 16:30 COFFEE BREAK  
16:30 - 17:30 KEYNOTE: Deciphering Oncohistone Pathogenesis in Human Cancers - Naba Jabado, Research Institute of the McGill University Health Center, Montreal- Chairs: Colin Crist and Michel Cayouette  
17:30 - 20:00 POSTER SESSION and "APERITIF"  

Tuesday, May 17, 2022

Time Event (+)
09:00 - 11:00 EPIGENETICS AND GENE REGULATORY NETWORKS - Chairs: Pierre-Yves Bourillot and Fabrice Lavial  
09:00 - 09:30 The H3K9 methyltransferase SETDB1 safeguards muscle stem cell identity - Fabien Le Grand, Institut Neuromyogène, Lyon  
09:30 - 10:00 Hematopoietic Lineage Determination by SWI/SNF Chromatin Remodeling Complexes - Julie Lessard, Institut de recherche en immunologie et en cancérologie, Université de Montréal  
10:00 - 10:15 A tight coupling between ribosome biogenesis and chromatin remodeling rewires embryonic stem cell fate - Mathieu Gabut, Centre de Recherche en Cancerologie de Lyon - Selected talk  
10:15 - 10:30 The comparative roadmaps of reprogramming and transformation unveiled that cellular plasticity is broadly controlled by Bcl11b and Atoh8 - Aurélia Huyghe, Cellular reprogramming, stem cells and oncogenesis Laboratory, Lyon -Selected Talk  
10:30 - 11:00 COFFEE BREAK  
11:00 - 11:30 Whole body regeneration requires a rewired embryonic gene regulatory network logic - Eric Rottinger, Institute for Research on Cancer and Aging, Nice  
11:30 - 12:30 BIO-ENGINEERING - Chairs: Stéphanie Gobert-Gosse and Anne Mey  
11:30 - 12:00 BioactiveCoatings: a new way to study cell signaling and differentiation - Catherine Picart, CEA/IRIG Grenoble  
12:00 - 12:15 Growth factors alone can induce a non-canonical differentiation of fibroblasts into functional neural progenitors - David Knapp, Institut de Recherche en Immunologie et en Cancerologie, Montreal - Selected talk  
12:15 - 12:30 The interplay between epithelial to mesenchymal transition and cell fate specification potentiates gastruloids self-organization - Alexandre Mayran, Institut Suisse de Recherches Expérimentales sur le Cancer (EPFL), Lausanne -Selected talk  
12:30 - 14:00 LUNCH & FREE VISIT OF POSTERS  
14:00 - 14:30 Modeling patient-derived glioblastoma with brain organoids and engineered neural tissue  - Erika Cosset, CRCL, Lyon  
14:30 - 15:00 Cardiovascular disease modelling using human pluripotent stem cells in organs-on-chip - Christine Mummery, Leiden University Medical Center  
15:00 - 17:30 ENVIRONMENT OF STEM CELLS - Chairs: Lydia Campos and Sylvain Lefort  
15:00 - 15:30 Cytoplasmic material exchange between sensory neurons in vivo - Valerie Wallace, University Health Network, Toronto  
15:30 - 15:45 Norrin/Frizzled4 signalling controls the microenvironment to suppress medulloblastoma - Nenad Pokrajac, Krembil Research Institute, Toronto - Selected talk  
15:45 - 16:00 Regulation of vascular cells in Duchenne Muscular Dystrophy - Dieuhuong Hoang, Institut Neuromyogene, Lyon - Selected talk  
16:00 - 16:30 COFFEE BREAK  
16:30 - 17:00 Healthy and malignant haematopoiesis: dynamic cells in an evolving environment - Cristina Lo Celso, Imperial College London  
17:00 - 17:30 Targeting muscle stem cells with bioactive lipids to enhance myogenesis in Duchenne Muscular Dystrophy - Nicolas Dumont, Centre de recherche du CHU Ste-Justine, Université de Montréal  
17:30 - 17:45 POSTER AWARDS & CLOSING REMARKS - Bénédicte Chazaud, Colin Crist and Michel Cayouette